Iodoacétamide
L'iodoacétamide est un composé organo-iodé de formule brute C2H4INO. C'est agent alkylant utilisé dans la cartographie des peptides. Son action est semblable à celle de l'acide iodoacétique. Il est communément utilisé pour se lier de façon covalente avec le groupe thiol de la cystéine afin que cette protéine ne forme pas de liaison disulfure,. Il est aussi utilisé dans les études sur l'ubiquitine comme inhibiteur des désubiquitinases (DUB) car il alkyle les résidus de cystéine sur le site actif des DUB. Comme beaucoup d'autres agents alkylants, l'iodacétamide est très toxique. Sur les souris de laboratoire, il a été montré qu'il peut provoquer des tumeurs de la peau et affecter négativement leur reproduction.

Ceci est un extrait de l'article Iodoacétamide de l'encyclopédie libre Wikipedia. La liste des auteurs est disponible sur Wikipedia.
Sur fr.wikipedia.org, l'article Iodoacétamide a été consulté 165 fois au cours des 30 derniers jours. (date: 18.10.2013)
Images pour Iodoacétamide
Miniature:
Original:
- Publicité -
Résultats de la recherche sur Google et Bing
1
>30
1
Iodoacétamide - Wikipédia
L'Iodoacétamide est un composé organo-iodé de formule brute C2H4INO. C'est agent alkylant utilisé dans la cartographie des peptides. Son action est ...
fr.wikipedia.org/wiki/Iodoac%C3%A9tamide
2
>30
2
Iodoacetamide - Wikipedia, the free encyclopedia
2-Iodoacetamide is an alkylating agent used for peptide mapping purposes. Its actions are similar to those of iodoacetate. It is commonly used to bind covalently  ...
en.wikipedia.org/wiki/Iodoacetamide
3
>30
3
Iodoacetamide BioUltra | Sigma-Aldrich
Sigma-Aldrich offers Sigma-I1149, Iodoacetamide for your research needs. Find product specific information including CAS, MSDS, protocols and references.
www.sigmaaldrich.com/catalog/product/sigma/i1149
4
>30
4
Iodoacetamide, Single-Use - Pierce
Introduction. Iodoacetamide is a sulfhydryl-reactive alkylating reagent used to block reduced cysteine residues for protein characterization and peptide mapping.
www.piercenet.com/instructions/2162099.pdf
5
>30
5
2-Iodoacetamide | 144-48-9 - Chemical Book
Visit ChemicalBook To find more 2-Iodoacetamide(144-48-9) information like chemical properties,Structure,melting point,boiling point,density,molecular formula ...
www.chemicalbook.com/ChemicalProductProperty_EN_CB4760867.htm
6
>30
6
The Specific Alkylation by Iodoacetamide of Histidine-12 in the ...
Abstract. Alkylation of ribonuclease A by iodoacetamide at pH 5.5 yields two products: inactive 3-carboxamidomethylhistidine-12-ribonuclease and fully active  ...
www.jbc.org/content/242/24/5807.abstract
7
>30
7
GE Healthcare Life Sciences "Iodoacetamide"
Ultrapure, proteomic-grade iodoacetamide is used for efficient alkylation of thiols while minimizing oxidation of the competing thiol pairs in protein samples.
www.gelifesciences.com/webapp/wcs/stores/servlet/productById/GELifeSciences/25900066
8
>30
8
Iodoacetamide-alkylated methionine can mimic neutral loss of ...
Iodoacetamide-alkylated methionine can mimic neutral loss of phosphoric acid from phosphopeptides as exemplified by nano-electrospray ionization ...
www.ncbi.nlm.nih.gov/pubmed/15912474
9
>30
9
LC/MS characterization of undesired products formed during ...
Many undesired by-products have been noticed during alkylation with iodoacetamide, a widely used derivatization reaction in proteomics for the determination ...
www.ncbi.nlm.nih.gov/pubmed/17206739
10
>30
10
Iodoacetamide | C2H4INO | ChemSpider
Structure, properties, spectra, suppliers and links for: Iodoacetamide.
www.chemspider.com/Chemical-Structure.3596.html
Résultats de la recherche pour "Iodoacétamide"
Google: env. 317.000
Iodoacétamide en science
20. Sapécine
iodoacetate iodoacetamide chromatographie electrophorese cysteine pont disulfure.
[PDF]Relations entre l'iodoacétamide, l'insuline et la synthèse ... - Karger
Institut de Biochimie médicale de l'Université de Genève ... éventuellement carboxylase [16] étaient atteints par l'Iodoacétamide comme in vitro, la synthèse.
Inhibition of CO2 fixation by iodoacetamide stimulates cyclic electron ...
28 Apr 2013... CNRS-Université Paris 6, Institut de Biologie Physico-Chimique, 13, rue ... Iodoacetamide reacts irreversibly with free -SH groups of cysteine ...
Iodoacetamide - BuyersGuideChem
Obtenir la liste des fournisseurs de Iodoacetamide et l'égalité produit. ... Avec le ferme soutien de l Université de Nanjing de la science et de la technologie.
[PDF]Action de l'iodoacétamide seule ou associée au ... - Karger
Adresse des auteurs: H. Bodur, S. Rous, L. Lüthi, Institut de Biochimie médicate de l'Université, 1211 Genève 4 (Suisse). L'Iodoacétamide peut porter atteinte à ...
Inhibition of CO2 fixation by iodoacetamide stimulates cyclic ... - Inist
Inhibition of CO2 fixation by iodoacetamide stimulates cyclic electron flow and ... ( 1) Unité Mixte de Recherche 7141 CNRS-Université Paris 6, Institut de ...
Inhibition of CO2 fixation by iodoacetamide ... - ResearchGate
Unité Mixte de Recherche 7141 CNRS-Université Paris 6, Institut de Biologie ... Iodoacetamide reacts irreversibly with free -SH groups of cysteine residues and ...
[PDF]universite paris xii val de marne faculté des ... - Biochimie12papy
On étudie l'inactivation irréversible de cette enzyme par l'Iodoacétamide. Pour cela on incube une aliquote d'enzyme en présence d'une concentration de 4 mM  ...
[PDF]Les acides aminés : Propriétés Physico-chimiques - Université ...
Année universitaire 2010/2011. Université Joseph Fourier de Grenoble - Tous droits réservés. UE1 : Biomolécules (1) ..... Iodoacétamide. CYS-SH. +. CYS-S CH.
Livres sur le terme Iodoacétamide
Proteomics Today: Protein Assessment and Biomarkers Using ...
Proteomics Today: Protein Assessment and Biomarkers Using ...
Mahmoud H. Hamdan, Pier G. Righetti, 2005
Subsequently, the same group (Galvani et al., 2001) has monitored the kinetics of protein alkylation by iodoacetamide over the period 0–24 h at pH 9. Alkylation reached ∼70% in the first 2 min, yet the remaining 30% required up to 6 h for ...
Techniques in Protein Modification
Techniques in Protein Modification
Roger L. Lundblad, 1994
The figure on the right shows the effect of pH on the second-order rate constant for the reaction between iodoacetamide and thioredoxin. (From Kallis. G.-B. and Holmgren. A.,/. Biol Chem., 255, 10261, 1980. With permission.) since the a-halo  ...
Advances in Chromatography
Advances in Chromatography
Phyllis R. Brown, Eli Grushka, 2003
A thorough investigation by ESI-MS demonstrated that indeed thiourea was competing with the free −SH groups of proteins for reaction and was scavenging iodoacetamide at an incredible rate (in approximately 5 min of incubation all ...
Organelle Proteomics
Organelle Proteomics
Delphine Pflieger et Jean Rossier, 2010
This is the first book to examine organelle proteomics in depth. It begins by introducing the different analytical strategies developed and successfully utilized to study organelle proteomes, and detailing the use of multidimensional liquid chromatography coupled to tandem mass spectrometry for peptide sample analysis. Detailed protocols are provid...
Bioconjugate Techniques
Bioconjugate Techniques
Greg T. Hermanson, 2013
R—SH Sulfhydryl-Containing Molecule Tetramethylrhodamine5-iodoacetamide Thioether Bond Formation formation. toward various sulfhydryl sites in proteins may be observed (Ajtai et al., 1992). The iodoacetyl group of both isomers reacts  ...
Proteome Research: Concepts, Technology and Application
Proteome Research: Concepts, Technology and Application
M.R. Wilkins, R.D. Appel, K.L. Williams, 2008
Poor alkylation efficiency can occur when using iodoacetamide as the alkylating agent unless care is taken to add iodoacetamide as a powder to the sample solution or it is dissolved in plain water and added it to the sample just at the moment ...
Développement des demandes de recherche Google
Entrées blog pour le terme
Iodoacétamide
bull's eye [cryptonatica affinis syn natica algida n beverlii n clausa consolidata n depressior n russa n septentrionalis] [arctic moonsnail] translation French | English-French dictionary | Reverso
bull's eye [cryptonatica affinis syn natica algida n beverlii n clausa consolidata n depressior n russa n septentrionalis] [arctic moonsnail] translation french, English - French dictionary, meaning, see also 'bull bar',bull elephant',bull market',bull terrier', example of use, definition, conjugation, Reverso dictionary
dictionary.reverso.net/english-french/bull's%20eye%20[cryptonatica%20affinis%20syn%20natica%20algida%20n%20beverlii%20n%20clausa%20consolidata%20n%20depressior%20n%20russa%20n%20septentrionalis]%20[arctic%20moonsnail]
common tobacco [nicotiana rustica syn n pavonii n texana] translation French | English-French dictionary | Reverso
common tobacco [nicotiana rustica syn n pavonii n texana] translation french, English - French dictionary, meaning, see also 'commoner',commonly',Commons',common cold', example of use, definition, conjugation, Reverso dictionary
dictionary.reverso.net/english-french/common%20tobacco%20[nicotiana%20rustica%20syn%20n%20pavonii%20n%20texana]
n'sche translation French | English-French dictionary | Reverso
n'sche translation french, English - French dictionary, meaning, see also 'SCE',she',she-',schedule', example of use, definition, conjugation, Reverso dictionary
dictionary.reverso.net/english-french/n'sche
baz n translation French | English-French dictionary | Reverso
baz n translation french, English - French dictionary, meaning, see also 'bazooka',BA',baize',blaze', example of use, definition, conjugation, Reverso dictionary
dictionary.reverso.net/english-french/baz%20n
Hameed Kashmir Card Centre | Bridal LoungeBridal Lounge
Press Market, Chowk Mayo Hospital, Lahore Tel: 92-42-37215753
www.bridallounge.com/hameed-kashmir-card-centre/
1397-89-3 Amphotericin B, China 1397-89-3 Amphotericin B Manufacturers, China 1397-89-3 Amphotericin B Suppliers - Jinlan
We,China 1397-89-3 Amphotericin B Suppliers and China 1397-89-3 Amphotericin B Manufacturers, provide 1397-89-3 Amphotericin B product and the products related with China 1397-89-3 Amphotericin B - Jinlan
www.chinachemnet.com/50076/1397-89-3-1815405.html
EJC Search Results: keywords:"EST"
journals.ohiolink.edu/ejc/search.cgi?q=keywords:%22EST%22&start=4201
Amphotericin B CAS: 1397-89-3 China (Mainland) Pharmaceutical
Amphotericin B CAS: 1397-89-3,complete details about Amphotericin B CAS: 1397-89-3 provided by Sinosource Import & Export Corp.. You may also find other latest Amphotericin B CAS: 1397-89-3 selling and buying leads on weiku.com.
www.weiku.com/products/11117680/Amphotericin_B_CAS_1397_89_3.html
doripenem hydrate CAS: 364622-82-2 China (Mainland) Pharmaceutical
doripenem hydrate CAS: 364622-82-2,complete details about doripenem hydrate CAS: 364622-82-2 provided by Sinosource Import & Export Corp.. You may also find other latest doripenem hydrate CAS: 364622-82-2 selling and buying leads on weiku.com.
www.weiku.com/products/11117682/doripenem_hydrate_CAS_364622_82_2.html
123